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NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS
Official Journal of the Bulgarian Society of Neurosonology and Cerebral Hemodynamics
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NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 13, 2017, No. 2
Recently, we published data based on decreased calcitonin gene-related peptide levels in saliva of BMS patients, showing that trigeminal
may be the underlying cause of BMS .
between females and males varies from 3:1 to 16:1. Furthermore, up to 90% of female patients with BMS are perimenopausal, with typical onset from 3 years prior to 12 years post the beginning of menopause. Despite the large number of clinical and epidemiological studies, pathogenesis and aetiology of BMS remains unclear . Recent clinical, electrophysiological [4, 5] and histological  studies suggest that primary neuropathic dysfunction might be involved in the pathogenesis of BMS. On the other hand, a central mechanism with the involvement of dopamine receptors in the basal ganglia was suggested to play a role in the pathogenesis of the disease .
Recently, we published data based on decreased calcitonin gene-related peptide levels in saliva of BMS patients, showing that trigeminal nerve degeneration may be the underlying cause of BMS .
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