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NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS
Official Journal of the Bulgarian Society of Neurosonology and Cerebral Hemodynamics
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Search Results for “search_doc_txt.php” – NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS
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1.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, Vol. 1, 2005
,
,
,
Methods for quantitative evaluation of the autonomic
nervous
system
.
Hilz M, Dutsch M.
Methods for quantitative evaluation of the autonomic nervous system.
read the entire text >>
The main aspects of his scientific interests are infections and dystrophies of the
nervous
system
and Evolutional Neurology.
Prof. Georgiev is an author or co-author of more than 300 scientific publications in Bulgarian and foreign journals, lecturer in national and international congresses.
The main aspects of his scientific interests are infections and dystrophies of the nervous system and Evolutional Neurology.
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2.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 2, 2006, No. 1
,
,
,
Neuroanatomical and neurophysiological changes likely underlie reorganization of the central
nervous
system
and these changes are, in part, possible to characterize experimentally using imaging methods to evidence the post-stroke plasticity.
Yet the recovery after the stroke and consistent reorganization in the neural tissue takes many weeks and even many months. Recovery from strokes with identical initial clinical manifestations may vary greatly and our understanding of the recovery processes, though exponentially increased during last 10 years, is still very limited. Contrary to what was previously held as a fact, recent research advances have demonstrated that the adult human brain has a certain capacity for plastic reorganization and self-repair after a stroke. The mechanisms responsible for post-stroke recovery are complex and they operate at different levels, from signal transduction and gene transcription to synaptic and neural network level reorganization. The integrated use of functional neuroimaging techniques, at the same time trying to overcome the limitations of each specific methodology, is likely to shed much light on brain plasticity mechanisms.
Neuroanatomical and neurophysiological changes likely underlie reorganization of the central nervous system and these changes are, in part, possible to characterize experimentally using imaging methods to evidence the post-stroke plasticity.
Better understanding of these mechanisms can provide neurorehabilitation with powerful tools to help in designing and implementing new therapeutic approaches to stroke patients both in the acute and the chronic stages after a
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Vascular and humoral sympathetic
nervous
system
reactivity during mental arithmetic in primary Raynaud’s phenomenon.
Droste H, Wollersheim H, Reyenga J, Thien T.
Vascular and humoral sympathetic nervous system reactivity during mental arithmetic in primary Raynaud’s phenomenon.
read the entire text >>
In: Donaghy M (ed) Brain’s diseases of the
nervous
system
.
Warlow C. Stroke, transient ischemic attacks, and intracranial venous thrombosis.
In: Donaghy M (ed) Brain’s diseases of the nervous system.
Oxford University Press, 2001:775-896.
read the entire text >>
3.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 2, 2006, No. 2
,
,
,
Vascular and humoral sympathetic
nervous
system
reactivity during mental arithmetic in primary Raynaud’s phenomenon.
Droste H, Wollersheim H, Reyenga J, Thien T.
Vascular and humoral sympathetic nervous system reactivity during mental arithmetic in primary Raynaud’s phenomenon.
read the entire text >>
Cardiovascular autonomic
nervous
system
tests: Determination of norma� tive values and effect of confounding variables.
Gelber D, Pfeifer M, Dawson B, Schumer M.
Cardiovascular autonomic nervous system tests: Determination of norma� tive values and effect of confounding variables.
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J Autonomic
Nervous
System
J Autonomic Nervous System
read the entire text >>
4.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 3, 2007, No. 1
,
,
,
Embryonic stem cells and cell replacement therapies in the
nervous
system
.
Fluckiger A.C, Dehay C, Savatier P.
Embryonic stem cells and cell replacement therapies in the nervous system.
read the entire text >>
Here the neuronal control of the autonomous
nervous
system
is superimposed as (1) a negative feedback (based on the pressure receptors of the carotid sinus), and results in suppression of the cardiac output and systemic (aortic) blood pressure, and (2) as a positive feedback to the
while maintaining the overall cerebral blood flow. The aforesaid local subsystems and the whole cerebral system are working as parts of the whole body circulation system, which driving forces are the cardiac output and systemic blood pressure. These directly influenced the pressure and blood flow at the beginning of the cerebral magistrals.
Here the neuronal control of the autonomous nervous system is superimposed as (1) a negative feedback (based on the pressure receptors of the carotid sinus), and results in suppression of the cardiac output and systemic (aortic) blood pressure, and (2) as a positive feedback to the
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Military Medical Academy
Clinic of Functional Diagnostics of Nervous System Military Medical Academy
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5.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 3, 2007, No. 2
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
of
Nervous
System
Military Medical Academy
of Nervous System Military Medical Academy
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Clinics for Functional Diagnostics of
Nervous
System
Clinics for Functional Diagnostics of Nervous System
read the entire text >>
6.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 4, 2008, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
of
Nervous
System
of Nervous System
read the entire text >>
In Bodo G, Lang J, Spellenberg S, (eds) The vegetative
nervous
system
and the vestibular, visual and cochlear functions.
Ivanov I, Ignatova K, Kolev O. Blood pressure and pulse rate changes induced by strong noise in patients with arterial hypertension.
In Bodo G, Lang J, Spellenberg S, (eds) The vegetative nervous system and the vestibular, visual and cochlear functions.
Budapest: ONO Section of the Hungarian Otorhinolaryngological Society, 1985, 392-395.
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The acquired metabolic disorders of the
nervous
system
.
Ropper A, Brown R.
The acquired metabolic disorders of the nervous system.
In: H, Brown RH (eds) Adams and Victor’s principles of neurology. McGraw – Hill, Medical Publishing Division New York, 2005, 959-982.
read the entire text >>
Nitric oxid signaling in the central
nervous
system
.
Gartwaite J, Boulton CL.
Nitric oxid signaling in the central nervous system.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System Military Medical Academy – Sofia, Bulgaria
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System Military Medical Academy – Sofia
read the entire text >>
7.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 4, 2008, No. 2
,
,
,
of
Nervous
System
Military Medical Academy 3 Georgi Sofiiski Blvd 1606 Sofia, Bulgaria
of Nervous System Military Medical Academy 3 Georgi Sofiiski Blvd 1606 Sofia, Bulgaria
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Both methods are applied for early diagnosis of various (mainly vascular) disorders of the central
nervous
system
and other human systems by imaging of the vessel’s network (arteries, veins and capillaries) of the pathology process, as well as for control of the treatment and prognosis of the disease.
The aim of the review is to introduce two new imaging methods – diffusion and perfusion tests for detection of morphological and functional changes in vascular and other diseases of the brain and other human organs and systems. The diffusion test is performed by magnetic resonance imaging (MRI), and the perfusion test – using multidetectional computer tomography (CT).
Both methods are applied for early diagnosis of various (mainly vascular) disorders of the central nervous system and other human systems by imaging of the vessel’s network (arteries, veins and capillaries) of the pathology process, as well as for control of the treatment and prognosis of the disease.
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c.), Fundamental Neurosciences, hyperbaric influence on the
nervous
system
, different neuroenzimes.
Prof. Mavlov is a scientist and clinician with wide interests and high erudition. He is an author of more than 200 scientific works, including different areas of the Clinical Neurology (higher cerebral functions, cerebrovascular diseases, degenerative disorders e. t.
c.), Fundamental Neurosciences, hyperbaric influence on the nervous system, different neuroenzimes.
read the entire text >>
8.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 5, 2009, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
The vegetative
nervous
system
and the vestibular, visual and
Ivanov I, Ignatova K, Kolev O. Blood pressure and pulse rate changes induced by strong noise in patients with arterial hypertension. In Bodo G, Lang J, Spellenberg S, eds.
The vegetative nervous system and the vestibular, visual and
read the entire text >>
Normal aging in the central
nervous
system
: quantitative MR diffusion-tensor analysis.
Abe O, Aoki S, Hayashi N, Yamada H, Kunimatsu A, Mori H, Yoshikawa T, Okubo T, Ohtomo К.
Normal aging in the central nervous system: quantitative MR diffusion-tensor analysis.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
9.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 5, 2009, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Titianova, MD, PhD, DSc Clinic of Functional Diagnsotics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnsotics of Nervous System
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Paraneoplastic syndromes affecting the
nervous
system
.
Darnell RB, Posner JB.
Paraneoplastic syndromes affecting the nervous system.
read the entire text >>
Paraneoplastic syndromes involving the
nervous
system
.
Robert BD, Jerome PB.
Paraneoplastic syndromes involving the nervous system.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Paraneoplastic syndromes affecting the
nervous
system
.
Darnell RB, Posner JB.
Paraneoplastic syndromes affecting the nervous system.
read the entire text >>
Paraneoplastic syndromes involving the
nervous
system
.
Robert BD, Jerome PB.
Paraneoplastic syndromes involving the nervous system.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
10.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 6, 2010, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
11.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 6, 2010, No. 2
,
,
,
Proposals for upgrading the postgraduate training programs "Neurosonology” and “Investigation of Autonomic
Nervous
System
” were also made.
in carotid pathology, published in Issue 2/2008 of the Journal. It helps the experts to follow uniform rules for sonographic examinations and result interpretation, related to target groups, study frequency, location, type and severity of vascular pathology, follow up of the effect of treatment.
Proposals for upgrading the postgraduate training programs "Neurosonology” and “Investigation of Autonomic Nervous System” were also made.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
They account for approximately 10% of all tumors of the central
nervous
system
.
All tumors originating from the spinal cord, adjacent spinal nerve roots and spinal cord meninges are determined as spinal cord tumors.
They account for approximately 10% of all tumors of the central nervous system.
About 30% of the spinal cord tumors are intramedullary. The most common extramedullary tumors are meningioma, neurinoma and filum terminale ependymoma [14]. The surgical treatment of spinal cord tumors began in 1887, when Victor Horsley performed the first successful operation of a spinal cord meningioma. In 1913 Freiher von Eiselsberg performed in Vienna the first successful operation of an intramedullary tumor [17]. Presently, microsurgical techniques play an important role in the treatment of most tumors, as modern imaging examinations precede the detailed preoperative planning.
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
Hyperintense basal ganglia on T1-weighted MR images in a patient with central
nervous
system
lupus and chorea.
Kashihara K, Nakashima S, Kohira I, Shohmori T, Fujiwara Y, Kuroda S.
Hyperintense basal ganglia on T1-weighted MR images in a patient with central nervous system lupus and chorea.
read the entire text >>
Diffuse central
nervous
system
lupus involving white matter, basal ganglia, thalami and brainstem.
Shibata M, Kibe T, Fujimoto S, Ishikawa T, Murakami M, Ichiki T.
Diffuse central nervous system lupus involving white matter, basal ganglia, thalami and brainstem.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
12.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 7, 2011, No. 1
,
,
,
New indications have been approved and new conceptions for the presented disorders of the central
nervous
system
have been formulated or confirmed.
This short review of the contemporary assessment of language functions and their impairment FNM demonstrates several trends. The application of these methods has increased for the last years.
New indications have been approved and new conceptions for the presented disorders of the central nervous system have been formulated or confirmed.
The specific advantages of every FNM would allow adequate diagnostic schemes to be created in specific clinical situations, but their application is still limited.
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13.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 7, 2011, No. 2
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
system
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous system, Military Medical Academy – Sofia
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
system
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous system, Military Medical Academy – Sofia
read the entire text >>
Fingolimod mediates its therapeutic effects through the immune
system
and directly on the central
nervous
system
(CNS).
(fingolimod), is the first oral drug licensed by the European Medicines Agency as a single disease modifying therapy in highly active relapsing remitting multiple sclerosis (MS).
Fingolimod mediates its therapeutic effects through the immune system and directly on the central nervous system (CNS).
Fingolimod reduces the recirculation of auto-reactive central memory Tcells and their infiltration in the CNS, where they would cause neurodegeneration. Peripheral lymphocyte count reduction is reversible and reflects the reversible retention of circulating lymphocytes in lymph nodes, but not their depletion. Two large, phase 3 trials – TRANSFORMS and FREEDOMS demonstrated that fingolimod improved the clinical outcome for MS patients – reduced the annualized relapse rate, decreased the risk of confirmed disability progression and reduced the number and volume of brain lesions on MRI images.
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Fingolimod exerts its therapeutic action through influencing the immune
system
and direct effects in the central
nervous
system
(CNS).
Fingolimod exerts its therapeutic action through influencing the immune system and direct effects in the central nervous system (CNS).
During immunosurveillance naive B and T lymphocytes regularly circulate between blood and lymphatic system via lymph nodes in search of foreign antigens. Sphingosine 1phosphate (S1P) concentration gradient between lymph nodes and body fluids regulates this process via interaction between S1P and S1PR expressed on lymphocytes [5]. When an antigen is encountered in lymph nodes, S1P
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Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
read the entire text >>
14.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 8, 2012, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Peripheral
nervous
system
was studied by Nicolet Viking Quest.
Peripheral nervous system was studied by Nicolet Viking Quest.
Stimulation electromyography (EMG) on n. tibialis was performed and a compound muscle action potential (CMAP) of m. gastrocnemius medialis and lateralis with bipolar surface electrodes was carried out. Standard quantitative EMG with concentric needle electrode was also performed. Different characteristics of CMAP were evaluated (latency time, amplitude and area of response), as well as spontaneous activity of
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Magnetic stimulation (MS) is a noninvasive neurophysiologic method of studying the functions and relations in
nervous
system
using electromagnetic induction.
Magnetic stimulation (MS) is a noninvasive neurophysiologic method of studying the functions and relations in nervous system using electromagnetic induction.
It is divided on transcranial (TMS) and peripheral (PMS) depending on target anatomical structures. Brain cortex, nerve roots, plexuses, cranial and peripheral nerves stimulation by rapidly changing magnetic field leads to depolarization and hyperpolarization of neurons and induces well detectable weak electric currents. Since its introduction in 1985 this method has undergone a large development and has given new perspectives in pathophysiology, diagnostics and therapy of different diseases in Neurology, Psychiatry and Neurosurgery.
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Clinic of Functional Diagnostics of
Nervous
System
Clinic of Functional Diagnostics of Nervous System
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It could be present in patients with pure autonomic dysfunction, other forms of autonomic
nervous
system
dysfunction and with volume depletion.
≥ 20 mmHg and diastolic BP ≥ 10 mmHg is observed during the first 3 min after standing [5].
It could be present in patients with pure autonomic dysfunction, other forms of autonomic nervous system dysfunction and with volume depletion.
Initial orthostatic hypotension is characterized by a fall in BP > 40 mmHg immediately upon standing with spontaneous and rapid normalization of BP, making the period with hypotension and symptoms short (< 30 sec) [20]. Delayed (progressive) orthostatic hypotension is common among elderly patients and is observed between the 3rd and 30th min of erect positioning. It could be attributed to age-associated compensatory reflex dysfunction and to increased myocardial and arterial stiffness, which in turns increases the susceptibility to changes in preload [19]. Delayed orthostatic hypotension is characterized with slow and progressive decrease in BP after standing and the absence of reflex bradycardia (vagal reaction) differentiates it from reflex syncope.
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The traditional concept that the central
nervous
system
(CNS) does not regenerate after injury evolved over the last 15 years.
The traditional concept that the central nervous system (CNS) does not regenerate after injury evolved over the last 15 years.
Numerous surveys reveal that even limited, the ability of the human brain to reorganize itself continues throughout life which is associated with brain plasticity on two functional levels: sensorimotor cortex (cortex plasticity) and neural network (neural plasticity). Drug and non-drug effects of treatment model the brain plasticity and facilitate the process of structural and functional brain reorganization which determines the ability of continuous functional recovery following brain injury [32]. The recovery potential increases when combining motor retraining, pharmacotherapy, stimulating techniques and cell therapy [20]. The changes in brain activity can be objectified by appropriate functional neuroimaging and electrophysiological methods [13].
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15.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 2, 2012, No. 2
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
read the entire text >>
Changes in the central
nervous
system
can be objectified with different functional neuroimaging and electrophysiological methods [1, 7, 15].
It is known that although limited, the ability of the human brain to reorganize continues throughout life which is associated with brain plasticity on two functional levels: sensorimotor cortex (cortical plasticity) and neuronal network (neuronal plasticity).
Changes in the central nervous system can be objectified with different functional neuroimaging and electrophysiological methods [1, 7, 15].
Recently, similar studies have established bilateral changes in motor control after stroke in which the participation of non-paretic side is proportional to the severity of brain injury [2, 3, 7, 14] and is associated with functional and
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Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Prof. E.
Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
– Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System – Military Medical Academy – Sofia,
read the entire text >>
Animal studies show the positive effect of hypothermia in central
nervous
system
injuries.
The aim of the treatment of brain and/or spinal cord injuries is the recovering of adequate perfusion; surgical evacuation of hematomas (if necessary) and oedema prophylaxis.
Animal studies show the positive effect of hypothermia in central nervous system injuries.
Basic science evidence also suggests that cooling affects many secondary biochemical cascades that are activated after acute injury. The potential benefit of this non-specific therapy is based on the observation that hypothermia reduces brain metabolism and energy consumption which might be feasible for improving the outcome of the injury [2, 19]. Comparing with the pharmacologic treatment which acts to a single neurochemical process, hypothermia interferes and inhibits multiple pathological processes simultaneously acting non-specifically. The results from the studies in humans are quite controversial and inconsistent. The results are difficult to interpret due to the limited number of patients, lack of controls, concomitant surgical procedures or concomitant use of drugs etc.
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of
Nervous
System
Military Medical Academy
of Nervous System Military Medical Academy
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Clinic of Functional Diagnostics of
Nervous
System
– Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System – Military Medical Academy – Sofia,
read the entire text >>
Minimal decrease of body temperature is known to be well tolerated leading to a significant reduction of pathologic pathways in the brain as well as to improvement of the
nervous
system
functions [14, 20, 25] while febrility and subfebrility in the first days after the stroke are associated with untoward clinical outcomes [20].
Therapeutic hypothermia (TH) is one of the most investigated neuroprotective method which prevents the neurons from cell’s death in a status of cerebral ischemia [22].
Minimal decrease of body temperature is known to be well tolerated leading to a significant reduction of pathologic pathways in the brain as well as to improvement of the nervous system functions [14, 20, 25] while febrility and subfebrility in the first days after the stroke are associated with untoward clinical outcomes [20].
It is presumed that the therapeutic hypothermia exerts its effect by influencing of metabolic processes in a neuron – a decrease of body temperature to 35°–30°C is leading to a reduction of oxygen consumption and CO
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of
Nervous
System
Military Medical Academy
of Nervous System Military Medical Academy
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Ekaterina Titianova, MD, PhD, Head of the Department „Functional Diagnostics of
Nervous
System
“ in MMA – Sofia and Chairman of the Bulgarian Association of Neurosonology and Cerebral Hemodynamics and others.
– Sofia, Prof. Soo-Bong Choi, Professor Adel Abdul Aziz al-Sayed, Professor Leo Pruimbum, Prof. Dr.
Ekaterina Titianova, MD, PhD, Head of the Department „Functional Diagnostics of Nervous System“ in MMA – Sofia and Chairman of the Bulgarian Association of Neurosonology and Cerebral Hemodynamics and others.
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of
Nervous
System
Military Medical Academy Blvd “Georgi Sofiiski” 3 1606 Sofia, Bulgaria
of Nervous System Military Medical Academy Blvd “Georgi Sofiiski” 3 1606 Sofia, Bulgaria
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16.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 9, 2013, No. 1
,
,
,
– Neurologist, Head of the Clinic “Functional Diagnostics of
Nervous
System
” at the Military Medical Academy – Sofia, Acting Head of Department “Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health” at the Faculty of Medicine of Sofia University “St.
– Neurologist, Head of the Clinic “Functional Diagnostics of Nervous System” at the Military Medical Academy – Sofia, Acting Head of Department “Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health” at the Faculty of Medicine of Sofia University “St.
Kliment Ohridski” and President of the Bulgarian Society of Neurosonology and Cerebral Hemodynamics.
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In 1983 she joined the Department for Diencephalic Pathology and Autonomic
Nervous
System
Diseases at the 3rd Clinic of Neurology (St.
Ljudmila Zaprianova, a worthy woman, a dedicated doctor and an excellent teacher. She was borne on June 6, 1958 in Sofia. She graduated from the High Medical School in Sofia in 1982 with excellent grades. Her professional career began in the Hospital of the Ljubimez town. After winning a competitive examination for Assistant Professor at the Department of Neurology of the Medical University she worked successively at the Alexandrovska and the ISUL (Tzaritza Jovanna) Hospitals.
In 1983 she joined the Department for Diencephalic Pathology and Autonomic Nervous System Diseases at the 3rd Clinic of Neurology (St.
Naum Hospital) where she worked until her death.
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During her work as a clinician she was approved as a competent and respected professional in the diagnostics and treatment of the diseases of autonomic
nervous
system
and borderline endocrinology and psychiatry pathological conditions.
“Neurovegetative and Neuroendocrine Aspects of the Biological StressResponse in Patients with Hypothalamic Syndromes” and acquired the scientific degree “Doctor”. She was an author of a number of publications in the field of the autonomic physiology and pathology.
During her work as a clinician she was approved as a competent and respected professional in the diagnostics and treatment of the diseases of autonomic nervous system and borderline endocrinology and psychiatry pathological conditions.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
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of
Nervous
System
Military Medical Academy 3, “Georgi Sofiiski” Blvd.
of Nervous System Military Medical Academy 3, “Georgi Sofiiski” Blvd.
1606 Sofia, Bulgaria
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17.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 9, 2013, No. 2
,
,
,
Early Physiotherapy Intervention for Preterm Neonates with Hypoxic Impairment of the Central
Nervous
System
.
Early Physiotherapy Intervention for Preterm Neonates with Hypoxic Impairment of the Central Nervous System.
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military
Clinic of Functional Diagnostics of Nervous System, Military
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia,
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To study central
nervous
system
changes in patients
To study central nervous system changes in patients
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with vascular and autonomic
nervous
system
disorders.
with vascular and autonomic nervous system disorders.
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EARLY PHYSIOTHERAPY INTERVENTION FOR PRETERM NEONATES WITH HYPOXIC IMPAIRMENT OF THE CENTRAL
NERVOUS
SYSTEM
EARLY PHYSIOTHERAPY INTERVENTION FOR PRETERM NEONATES WITH HYPOXIC IMPAIRMENT OF THE CENTRAL NERVOUS SYSTEM
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The goal of this paper is to evaluate whether early physiotherapy intervention (EPI) that started immediately after birth has a positive outcome for premature neonates with hypoxic impairments of the central
nervous
system
(CNS) who are at risk of developing motor disorders.
The goal of this paper is to evaluate whether early physiotherapy intervention (EPI) that started immediately after birth has a positive outcome for premature neonates with hypoxic impairments of the central nervous system (CNS) who are at risk of developing motor disorders.
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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18.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 10, 2014, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy Sofia,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
19.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 10, 2014, No. 2
,
,
,
Primary investigation areas: cerebral vascular disease, cerebral hemodynamics, neurosonology and syndrome of orthostatic intolerance / autonomic
nervous
system
; Participated in several investigation projects with other national and international centres, on the described areas, besides coordinating some clinical trials; Organized 93 courses and meetings, some of them international; Held 289 lectures and participated in 276 in scientific presentations.
Coordinator of the cerebrovascular investigation of the Unit of Cardiovascular Investigation of FMUP (since 2007).
Primary investigation areas: cerebral vascular disease, cerebral hemodynamics, neurosonology and syndrome of orthostatic intolerance / autonomic nervous system; Participated in several investigation projects with other national and international centres, on the described areas, besides coordinating some clinical trials; Organized 93 courses and meetings, some of them international; Held 289 lectures and participated in 276 in scientific presentations.
She is author of 197 papers published as abstracts and 55 published as full-texts in national and international journals, 5 chapters of books and edited 4 scientific publications and has received 6 scientific awards. She collaborates with various national and international work groups, within both clinical and investigation projects.
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She is a Head of the Clinic of Functional Diagnostics of
Nervous
System
at the Military Medical Academy Sofia (since 2005) and Academician of the Bulgarian Academy of Sciences and Arts (since 2012).
Acad. Prof. Ekaterina Titianova, MD, PhD, DSc is Professor of Neurology and Faculty member of the Faculty of Medicine of Sofia University "St. Kl. Ohridski".
She is a Head of the Clinic of Functional Diagnostics of Nervous System at the Military Medical Academy Sofia (since 2005) and Academician of the Bulgarian Academy of Sciences and Arts (since 2012).
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the Central
Nervous
System
: Physical Principles, Clinical Applications, and Emerging Techniques.
the Central Nervous System: Physical Principles, Clinical Applications, and Emerging Techniques.
First ed: John Wiley & Sons, Inc; 2014: 33-65.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
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As part of the central
nervous
system
the optic nerve is surrounded by cerebrospinal fluid and by meninges, and any changes of the intracranial pressure have an influence on ONSD.
As part of the central nervous system the optic nerve is surrounded by cerebrospinal fluid and by meninges, and any changes of the intracranial pressure have an influence on ONSD.
Geeraerts et al. suggested normal average values for the ONSD of 5.1±0.5 mm. ONSD values between 5.7 and 5.9 mm represent risk marker for increased intracranial pressure (ICP) particularly in patients with intracranial bleeding or head trauma (Fig. 4B) [29].
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20.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 11, 2015, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy Sofia,
read the entire text >>
of
Nervous
System
, Military Medical Academy,
of Nervous System, Military Medical Academy,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy Sofia,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy Sofia,
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As part of the central
nervous
system
the optic nerve is surrounded by cerebrospinal fluid and meninges.
In neurology field the ultrasound multimodal imaging of ocular structures contributes for evaluation of the type, location and severity of optic disc and optic nerve edema and their differentiation from pure ocular diseases.
As part of the central nervous system the optic nerve is surrounded by cerebrospinal fluid and meninges.
Any changes of the intracranial pressure have an influence on optic nerve/optic sheath ( ONSD) diameter (normal average values of 5.1±0.5 mm [1, 3, 4]). The sensitivity of transorbital ultrasound is 90% and its specificity – 85% for prediction of increased intracranial pressure. Decreased ONSD bellow 4.7 mm could be associated with intracranial hypotension, either idiopathic or iatrogenic [9].
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of
Nervous
System
, Military Medical Academy,
of Nervous System, Military Medical Academy,
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Sergey Nikolaev (Russia) conducted the practical exercises in patients with neuromuscular diseases and injuries of the peripheral
nervous
system
, assisted by Galia Nikolaeva, MD (Pavlikeni) and Albena Antimova, MD (Pleven).
At EMG section Assoc. Prof. Dr.
Sergey Nikolaev (Russia) conducted the practical exercises in patients with neuromuscular diseases and injuries of the peripheral nervous system, assisted by Galia Nikolaeva, MD (Pavlikeni) and Albena Antimova, MD (Pleven).
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
21.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 11, 2015, No. 2
,
,
,
For the past 10 years BSNCH has established itself as a respectable scientific organization in the field of Neurology and Neurosonology, introducing the European and world standards in ultrasound diagnostics of the
nervous
system
and of therapeutic ultrasound in Neurology.
For the past 10 years BSNCH has established itself as a respectable scientific organization in the field of Neurology and Neurosonology, introducing the European and world standards in ultrasound diagnostics of the nervous system and of therapeutic ultrasound in Neurology.
The society has grown in membership, expanded its scientific, educational and practical activity and imposed a policy of continuous post-graduate training and professional advancement of its members.
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It is part of the idea of “Balkan Neurosonolgy”, uniting scientific and practical interests in the field of ultrasound diagnosis of the
nervous
system
in the countries of the Southeast Europe.
Since 2015 the scientific Journal “Neurosonology and Cerebral Hemodynamics” creates the rubric “Serbian Neurosonology” edited by Prof. Nadezhda Sternic and Assoc. prof. Milija Mijajlovic from Serbia.
It is part of the idea of “Balkan Neurosonolgy”, uniting scientific and practical interests in the field of ultrasound diagnosis of the nervous system in the countries of the Southeast Europe.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria
read the entire text >>
autonomic
nervous
system
, hand-arm vibration syndrome,
autonomic nervous system, hand-arm vibration syndrome,
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Hyperreactivity during orthostatism and cold test were established in the primary Raynaud’s phenomenon patients, confirming the increased activity of sympathetic
nervous
system
.
Increased sympathetic and decreased parasympathetic modulation at rest in all patients with Raynaud's phenomenon was established. Abnormal heart rate variability with low power spectral density in the LF and HF components and reduction of the LF/HF ratio were obtained, pointing to reduced parasympathetic control in patients with scleroderma and Raynaud’s phenomenon. The measurements of cardiac vagal and adrenergic autonomic responses by deep breathing established reduced heart rate variability in the patients with hand-arm vibration syndrome and scleroderma, while the LF power is higher in the patients with hand-arm vibration syndrome than in the control subjects. The cardiac autonomic responses to orthostatism showed an increased sympathetic reactivity in the patients with hand-arm vibration syndrome and reduced reactivity in the patients with scleroderma.
Hyperreactivity during orthostatism and cold test were established in the primary Raynaud’s phenomenon patients, confirming the increased activity of sympathetic nervous system.
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Spectral analysis of heart rate variability is a noninvasive method for quantitative evaluation of neural cardiovascular control and study of changes in the activity of the autonomic
nervous
system
at rest and during functional effects.
Spectral analysis of heart rate variability is a noninvasive method for quantitative evaluation of neural cardiovascular control and study of changes in the activity of the autonomic nervous system at rest and during functional effects.
The components of the heart rate variability assess the extent of the autonomic modulation and reflect distortions in baroreflex activity and autonomic dysfunction. Heart rate variability in short electrocardiographic recordings shows three typical peaks in the very low (0 to 0.04 Hz; VLF), low (0.04 to 0.15 Hz; LF) and respiratory or high (0.15 to 0.40 Hz; HF) frequency bands. Respiratory HF frequencies of R-R interval fluctuations reflect vagal efferent pathway to the heart, i.e. fluctuations in vagal activity. Low frequencies (LF) of the R-R intervals characterize sympathetic neural spectrum [11].
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The two parts of the autonomic
nervous
system
are controlled and balanced [3].
Heart rate variability in short electrocardiographic recordings shows three typical peaks in the very low (0 to 0.04 Hz; VLF), low (0.04 to 0.15 Hz; LF) and respiratory or high (0.15 to 0.40 Hz; HF) frequency bands. Respiratory HF frequencies of R-R interval fluctuations reflect vagal efferent pathway to the heart, i.e. fluctuations in vagal activity. Low frequencies (LF) of the R-R intervals characterize sympathetic neural spectrum [11]. Fluctuations in vagal and sympathetic neural activity at rest and under external influences vary over time and are in constant interaction.
The two parts of the autonomic nervous system are controlled and balanced [3].
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Several studies show dysfunctions of the autonomic
nervous
system
in hand-arm vibration syndrome (HAVS) besides the characteristic peripheral vascular, neurological and musculoskeletal disorders in the upper limbs [2, 5].
Several studies show dysfunctions of the autonomic nervous system in hand-arm vibration syndrome (HAVS) besides the characteristic peripheral vascular, neurological and musculoskeletal disorders in the upper limbs [2, 5].
Hyperreactivity of the sympathetic nervous system in hand-arm vibration syndorme patients during cold impact is established by elevated serum catecholamines [14].
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Hyperreactivity of the sympathetic
nervous
system
in hand-arm vibration syndorme patients during cold impact is established by elevated serum catecholamines [14].
Several studies show dysfunctions of the autonomic nervous system in hand-arm vibration syndrome (HAVS) besides the characteristic peripheral vascular, neurological and musculoskeletal disorders in the upper limbs [2, 5].
Hyperreactivity of the sympathetic nervous system in hand-arm vibration syndorme patients during cold impact is established by elevated serum catecholamines [14].
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Hyperreactivity to orthostatic and cold tests was observed in pRP, confirming increased activity of the sympathetic
nervous
system
.
Hemodynamics in postural changes causes autonomic neural responses of the cardiovascular system, which buffers the fluctuations in blood pressure and causes baroreflex-mediated effects [12]. Cardiovascular autonomic functions in response to gravity-related baroreceptor stimulation showed enhanced sympathetic response in the first control and second vRP groups and suppressed reactivity in the fourth sclRP group.
Hyperreactivity to orthostatic and cold tests was observed in pRP, confirming increased activity of the sympathetic nervous system.
Patients with pRp have normal heart rate variability, but sympathetic hyperactivity to functional stimulation.
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Responses of sympathetic
nervous
system
to cold exposure in vibration syndrome subjects and agematched healthy controls.
Nakamoto M.
Responses of sympathetic nervous system to cold exposure in vibration syndrome subjects and agematched healthy controls.
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Pancera P, Sansone S, Presciuttini B, Montagna L, Ceru S, Lunardi C, Lechi A Autonomic
nervous
system
dysfunction in sclerodermic and primary Raynaud's phenomenon.
Pancera P, Sansone S, Presciuttini B, Montagna L, Ceru S, Lunardi C, Lechi A Autonomic nervous system dysfunction in sclerodermic and primary Raynaud's phenomenon.
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A modern introduction to the study of the autonomic
nervous
system
is presented.
The contemporary neurosonology is presented shortly, but maximally detailed and perfectly illustrated. Along with the latest innovations in the field of vascular pathology, neurosonology rises to a qualitatively new level certain areas of myology, neuroofthalmology, intraoperative navigation and even assists the diagnosis of neurodegenerative diseases.
A modern introduction to the study of the autonomic nervous system is presented.
In the near future the progress in this field will give us a new understanding and opportunities for the diagnosis and treatment of different somatic diseases. A substantive contribution is the section on the study and evaluation of gait – normal and pathological.
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Through its unique appearance and content the textbook fills a significant gap in the modern education literature as a contemporary practical guide on
nervous
system
diseases.
The textbook in general neurology is designed towards a wide audience with interests in neuroscience – students, physicians and specializing doctors in neurology and in physical and rehabilitation medicine, physiotherapists and healthcare professionals. It can be used by neurosurgeons, dentists, general practitioners, psychologists, psychiatrists and other specialists with interests in the field of neuroscience.
Through its unique appearance and content the textbook fills a significant gap in the modern education literature as a contemporary practical guide on nervous system diseases.
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Over the past decade the Bulgarian Society of Neurosonology and Cerebral Hemodynamics has established itself at home and abroad as a respectable scientific organization, leading in the introduction of international standards in ultrasound diagnostics of the
nervous
system
and therapeutic ultrasound in Neurology.
Over the past decade the Bulgarian Society of Neurosonology and Cerebral Hemodynamics has established itself at home and abroad as a respectable scientific organization, leading in the introduction of international standards in ultrasound diagnostics of the nervous system and therapeutic ultrasound in Neurology.
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We created a school in Neurosonology with a potential to offer highly qualified Bulgarian healthcare and European certified specialists in the field of ultrasound diagnostics of the
nervous
system
throughout the country.
Тhe history of BSNCH is rich on scientific events, creative activities and practical initiatives.
We created a school in Neurosonology with a potential to offer highly qualified Bulgarian healthcare and European certified specialists in the field of ultrasound diagnostics of the nervous system throughout the country.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
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In recent years transcranial sonography of brain parenchyma has proven its role in the diagnosis of several central
nervous
system
disorders manifested with brain atrophy.
In recent years transcranial sonography of brain parenchyma has proven its role in the diagnosis of several central nervous system disorders manifested with brain atrophy.
This method allows comparatively precise measurement of the third ventricle's diameter, which enlargement over 7 mm/10 mm in patients under/over 60 years is a sign of brain atrophy.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria
read the entire text >>
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
22.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 12, 2016, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria
read the entire text >>
of
Nervous
System
, Military Medical Academy,
of Nervous System, Military Medical Academy,
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria
read the entire text >>
of
Nervous
System
, Military Medical Academy,
of Nervous System, Military Medical Academy,
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Ekaterina Titianova, President of BSNCH and Head of the Clinic of Functional Diagnostics of
Nervous
System
at the Military Medical Academy – Sofia said: “Today we celebrate the 10
At the congress opening Acad. Prof.
Ekaterina Titianova, President of BSNCH and Head of the Clinic of Functional Diagnostics of Nervous System at the Military Medical Academy – Sofia said: “Today we celebrate the 10
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The guide is a navigator for selecting specialists in ultrasound diagnostics of the
nervous
system
throughout the country and is available online on the website of BSNCH.
The National Reference Book “Bulgarian Neurosonology. Who is Who” was presented at the Congress. The training neurosonology bases and Bulgarian neurosonologists by levels of competence are presented for the first time in this book.
The guide is a navigator for selecting specialists in ultrasound diagnostics of the nervous system throughout the country and is available online on the website of BSNCH.
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The main purpose of this new entity is focused on continuous training and exchange of best practices in the field of ultrasound diagnostics of the
nervous
system
in the region.
gists from Bulgaria, Serbia, Macedonia and Georgia was found.
The main purpose of this new entity is focused on continuous training and exchange of best practices in the field of ultrasound diagnostics of the nervous system in the region.
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Guest speaker at the event was academician Ekaterina Titianova, MD – Head of the “Clinic of Functional Diagnostics of
Nervous
System
” and Head of the Department “Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health” of the Medical Faculty of Sofia University “St.
On the first day over 80 doctors and pharmacists from the region attended the forum. Dr. Maria Radiykova – Chief Doctor of the local hospital, opened the seminar.
Guest speaker at the event was academician Ekaterina Titianova, MD – Head of the “Clinic of Functional Diagnostics of Nervous System” and Head of the Department “Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health” of the Medical Faculty of Sofia University “St.
Kliment Ohridski”. She presented the various neuropathy forms in diabetes mellitus, the reasons for their occurrence and some new treatment approaches, including strict glycemic control using insulin pumps, pathogenetic treatment with benfotiamine and alpha-lipoic acid, symptomatic treatment of neuropathic pain, foot hygiene, combined with appropriate exercise regimen. It was emphasized that as genetic dis-
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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23.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 12, 2016, No. 2
,
,
,
It is experimentally and clinically shown that it can be applied in treatment of ischemic vascular incidents, some neuro-degenerative diseases, tremors, epilepsy, peripheral
nervous
system
diseases, neuro-oncological processes, chronic pain, depressive and obsessive-compulsive disorders.
This review is dedicated to therapeutic abilities of the High Intensity Focused Ultrasound (HIFU) in Neurology.
It is experimentally and clinically shown that it can be applied in treatment of ischemic vascular incidents, some neuro-degenerative diseases, tremors, epilepsy, peripheral nervous system diseases, neuro-oncological processes, chronic pain, depressive and obsessive-compulsive disorders.
The method is non-invasive, has minimal side effects (no radiation or chemical load), allows a target impact in the disease focus area without a risk of damaging adjacent structures. Multicentric research is demanded to determine the optimal parameters, the safety limits, the indication and contraindication for its application in medicine and in neurology, in particular.
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The current review summarizes the potential of HIFU in the treatment and diagnostics of some
nervous
system
diseases.
Ultrasound diagnostics has been applied in medicine for decades as a diagnostic method [1]. With the introduction of high intensity focused ultrasound (HIFU) in experimental, preclinical and clinical conditions, new means of therapeutic ultrasonic influence on various diseases of human organs and systems have been unraveled in the recent years.
The current review summarizes the potential of HIFU in the treatment and diagnostics of some nervous system diseases.
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However limited it may be, HIFU's application in treatment of some
nervous
system
diseases comes where conventional therapeutic methods have failed.
However limited it may be, HIFU's application in treatment of some nervous system diseases comes where conventional therapeutic methods have failed.
Selection of diseases is dependent on the desired therapeutic effect and its localization, which is dealt with in the next section of this research.
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Experimentally and clinically HIFU is used in acute arterial thromboses, neurodegenerative diseases, epilepsy, peripheral
nervous
system
diseases, chronic pains, depressive and obsessive-compulsive disorders.
High Intensity Focused Ultrasound is a relatively novel non-invasive therapeutic method in neurology. It is approved in Europe, Korea and Russia for treatment of neuropathic pain, essential and Parkinson's tremor.
Experimentally and clinically HIFU is used in acute arterial thromboses, neurodegenerative diseases, epilepsy, peripheral nervous system diseases, chronic pains, depressive and obsessive-compulsive disorders.
Its main medical application is in somatic oncological diseases (breast cancer, kidney cancer, liver cancer, pancreatic cancer, etc.) Further research (experimental, preclinical and multicentric) is necessary to affirm unitary international criteria for applying HIFU in treatment of nervous system diseases.
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Its main medical application is in somatic oncological diseases (breast cancer, kidney cancer, liver cancer, pancreatic cancer, etc.) Further research (experimental, preclinical and multicentric) is necessary to affirm unitary international criteria for applying HIFU in treatment of
nervous
system
diseases.
High Intensity Focused Ultrasound is a relatively novel non-invasive therapeutic method in neurology. It is approved in Europe, Korea and Russia for treatment of neuropathic pain, essential and Parkinson's tremor. Experimentally and clinically HIFU is used in acute arterial thromboses, neurodegenerative diseases, epilepsy, peripheral nervous system diseases, chronic pains, depressive and obsessive-compulsive disorders.
Its main medical application is in somatic oncological diseases (breast cancer, kidney cancer, liver cancer, pancreatic cancer, etc.) Further research (experimental, preclinical and multicentric) is necessary to affirm unitary international criteria for applying HIFU in treatment of nervous system diseases.
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Production of Focal Destructive Lesions in the Central
Nervous
System
With Ultrasound.
Fry WJ, Mosberg WH, Barnard JW, Fry FJ.
Production of Focal Destructive Lesions in the Central Nervous System With Ultrasound.
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of
Nervous
System
, Military Medical Academy,
of Nervous System, Military Medical Academy,
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Since its foundation, BSNCH confirmed as a respected scientific organization, leading to the introduction of international standards in the ultrasonic diagnosis of the
nervous
system
as well as therapeutic ultrasound.
Since its foundation, BSNCH confirmed as a respected scientific organization, leading to the introduction of international standards in the ultrasonic diagnosis of the nervous system as well as therapeutic ultrasound.
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Some authors accept them as a new, so called "social
nervous
system
".
Mirror neurons are not yet a completely understood field of the brain and have not revealed all their possible applications. At present our knowledge about them is minimal, but is used for in-depth study of children with autism, cerebral rehabilitation, and explanation of various higher cortical functions such as memory, learning, speech, and empathy.
Some authors accept them as a new, so called "social nervous system".
Further investigations are needed to elucidate their real role in human life.
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Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
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Doctor Lilia Daskalova–Curzi is famous around the world for her contribution to the field of functional diagnosis of the central
nervous
system
.
Doctor Lilia Daskalova–Curzi is famous around the world for her contribution to the field of functional diagnosis of the central nervous system.
Her works are widely cited. She was a lecturer in Japan, USA, Brazil, Argentina, Chile as well as several European countries.
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
24.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 13, 2017, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia
read the entire text >>
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
read the entire text >>
25.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 13, 2017, No. 2
,
,
,
He specialized in Neurology, Clinical Neurophysiology, Neurological Intensive Care Medicine and Disorders of the Autonomic
Nervous
System
(ANS), and holds German board certificates in Neurology and Psychiatry and in Psychotherapy.
Prof. Dr. med. Dr.med.habil. Max J. Hilz studied medicine at the Universities of Cologne and Erlangen-Nuremberg in Germany. After he had defended his doctoral thesis in 1980, he trained in Anesthesiology and Intensive Care Medicine and in Ear-Nose-and–Throat diseases (1980–1982). He started his residency in Neurology and Psychiatry at the University of Erlangen-Nuremberg.
He specialized in Neurology, Clinical Neurophysiology, Neurological Intensive Care Medicine and Disorders of the Autonomic Nervous System (ANS), and holds German board certificates in Neurology and Psychiatry and in Psychotherapy.
He also passed the board examination of the American Board of Electrodiagnostic Medicine. He is licensed to practice medicine in Germany, the United Kingdom, and in the State of New York, USA.
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Prof. Hilz is experienced in the examination of small nerve fiber diseases and disorders of the autonomic
nervous
system
, including hereditary sensory and autonomic neuropathies, diabetic neuropathies, and Fabry disease, and central autonomic disorders.
Prof. Hilz is experienced in the examination of small nerve fiber diseases and disorders of the autonomic nervous system, including hereditary sensory and autonomic neuropathies, diabetic neuropathies, and Fabry disease, and central autonomic disorders.
He also served as an advisor to the European Medicines Agency, EMA, on issues related to autonomic nervous system dysfunction.
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He also served as an advisor to the European Medicines Agency, EMA, on issues related to autonomic
nervous
system
dysfunction.
Prof. Hilz is experienced in the examination of small nerve fiber diseases and disorders of the autonomic nervous system, including hereditary sensory and autonomic neuropathies, diabetic neuropathies, and Fabry disease, and central autonomic disorders.
He also served as an advisor to the European Medicines Agency, EMA, on issues related to autonomic nervous system dysfunction.
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Professor Hilz is a member of 16 national and international scientific societies and is on the board of several autonomic
nervous
system
societies.
Professor Hilz is a member of 16 national and international scientific societies and is on the board of several autonomic nervous system societies.
He currently co-chairs the Autonomic Nervous System Subspecialty Panel of the European Academy of Neurology, EAN. He also is PastPresident of the German Autonomic Society, Past-President of the European Federation of Autonomic Societies, and Past-Chair of the Autonomic Section of the American Academy of Neurology. He is ad hoc reviewer for more than 25 international scientific journals, a member of the editorial board of Clinical Autonomic Research, and Associate Clinical Editor of Autonomic Neuroscience: Basic and Clinical. He co-authored the guidelines of the German Neurological Society on syncope, the guidelines on erectile dysfunction and the guidelines of the German Diabetes Society on diabetic neuropathy. He has published more than 300 original and review articles in peer-reviewed journals and chapters in textbooks and presented his work at several hundred scientific conferences.
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He currently co-chairs the Autonomic
Nervous
System
Subspecialty Panel of the European Academy of Neurology, EAN.
Professor Hilz is a member of 16 national and international scientific societies and is on the board of several autonomic nervous system societies.
He currently co-chairs the Autonomic Nervous System Subspecialty Panel of the European Academy of Neurology, EAN.
He also is PastPresident of the German Autonomic Society, Past-President of the European Federation of Autonomic Societies, and Past-Chair of the Autonomic Section of the American Academy of Neurology. He is ad hoc reviewer for more than 25 international scientific journals, a member of the editorial board of Clinical Autonomic Research, and Associate Clinical Editor of Autonomic Neuroscience: Basic and Clinical. He co-authored the guidelines of the German Neurological Society on syncope, the guidelines on erectile dysfunction and the guidelines of the German Diabetes Society on diabetic neuropathy. He has published more than 300 original and review articles in peer-reviewed journals and chapters in textbooks and presented his work at several hundred scientific conferences.
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At present she is Professor of Neurology, Head of the Clinic of Functional Diagnostics of
Nervous
System
at the Military Medical Academy, Sofia, member of the Faculty Council and Head of the Department of Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health at the Medical Faculty of St Kliment Ohridski Sofia University.
At present she is Professor of Neurology, Head of the Clinic of Functional Diagnostics of Nervous System at the Military Medical Academy, Sofia, member of the Faculty Council and Head of the Department of Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health at the Medical Faculty of St Kliment Ohridski Sofia University.
Since 2013 she has been Academician of the Bulgarian Academy of Sciences and Arts and since 2015 – Academician of the Serbian Royal Academy. She is an expert at the Ministry of Health, the National Agency for Assessment and Accreditation at the Council of Ministers, and the National Health Insurance Fund of the Republic of Bulgaria. She is also an expert of the European Commission of the European Union.
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One neurotrophic factor in particular, the Brain Derived Neurotrophic Factor (BDNF), important for long term memory, affects neurons in central and peripheral
nervous
system
,
This famous sentence has been around for almost 2000 years. Back in the first and second century a.d., Decimus Iunius Iuvenalis, a Roman poet spoke of health, mental and physical, and their dependence on one another. But, it was not until the 1990s, when science allowed us to find proof for this idea, until the discovery of neurotrophic factors which changed around the way physical activity and brain plasticity were viewed. In 1986 Rita Levi Montalcini and Stanly Cohen received a Nobel Prize in medicine for the discovery of neurotrophins, proteins, belonging to a group of growth factors with a special effect on neurons. They signal nerve cells to grow, survive, and differentiate.
One neurotrophic factor in particular, the Brain Derived Neurotrophic Factor (BDNF), important for long term memory, affects neurons in central and peripheral nervous system,
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peripheral
nervous
system
, rehabilitation, ultrasound
peripheral nervous system, rehabilitation, ultrasound
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peripheral
nervous
system
, rehabilitation, ultrasound
peripheral nervous system, rehabilitation, ultrasound
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A multidimensional evaluation of peripheral
nervous
system
impairments improves diagnostic precision and therapeutic accuracy, even providing data about prognosis and disease evolution.
A wide literature shows that US integrates neurophysiological assessment in routine practice: by a combined use of electrodiagnosis and US we obtain more information than we do if they are separately used. If neurophysiology allows detecting nerve function, US provides detailed imaging of nerve morphology and size and of the surrounding structures.
A multidimensional evaluation of peripheral nervous system impairments improves diagnostic precision and therapeutic accuracy, even providing data about prognosis and disease evolution.
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Nerve US is a useful tool that provides important information in different peripheral
nervous
system
diseases: entrapment neuropathies [7,9], traumatic nerve lesions [8], nerve tumors, and immunemediated and hereditary neuropathies
Nerve US is a useful tool that provides important information in different peripheral nervous system diseases: entrapment neuropathies [7,9], traumatic nerve lesions [8], nerve tumors, and immunemediated and hereditary neuropathies
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
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of
Nervous
System
Military Medical Academy
of Nervous System Military Medical Academy
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It studies and applies complex medical approaches for compensating the damages of the
nervous
system
, offsetting the emerging functional
Neurorehabilitation is one of the main therapeutic approaches in the whole algorithm of treatment of DN.
It studies and applies complex medical approaches for compensating the damages of the nervous system, offsetting the emerging functional
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control [4]; improved orthostatic autoregulation by stimulating proprioception, activation of the sympathetic
nervous
system
and increase of the efficiency of the muscle pump (increased muscle strength of the lower limbs, positional and cardiovascular training) [5].
control [4]; improved orthostatic autoregulation by stimulating proprioception, activation of the sympathetic nervous system and increase of the efficiency of the muscle pump (increased muscle strength of the lower limbs, positional and cardiovascular training) [5].
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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26.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 14, 2018, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy – Sofia, Bulgaria
Clinic of Functional Diagnostics of Nervous System, Military Medical Academy – Sofia, Bulgaria
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It is assumed that these neurons are responsible for various functions of the
nervous
system
– empathy, imitation, prediction of others’ intentions, etc.
Mirror neurons are a newly discovered group of cells that are spontaneously activated when a person performs and/or monitors an action. The proof of their existence is a significant breakthrough in neurosciences.
It is assumed that these neurons are responsible for various functions of the nervous system – empathy, imitation, prediction of others’ intentions, etc.
Various new neurorehabilitation techniques, based on the concept of mirror neurons, have been developed for patients with paresis, paralysis and aphasia after damage to the central nervous system (primarily strokes and traumas). This therapy appears to be promising in Parkinson's disease, Moebius syndrome, cerebral paresis in children, phantom pain. There is a link between dysfunction of mirror neurons and autism spectrum diseases, as well as some neurodegenerative diseases such as Alzheimer's disease. Some scientists assume that mirror neurons form a new so-called “Social Nervous System”. Their role is to be further studied, evaluated and adequately applied in medical practice.
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Various new neurorehabilitation techniques, based on the concept of mirror neurons, have been developed for patients with paresis, paralysis and aphasia after damage to the central
nervous
system
(primarily strokes and traumas).
Mirror neurons are a newly discovered group of cells that are spontaneously activated when a person performs and/or monitors an action. The proof of their existence is a significant breakthrough in neurosciences. It is assumed that these neurons are responsible for various functions of the nervous system – empathy, imitation, prediction of others’ intentions, etc.
Various new neurorehabilitation techniques, based on the concept of mirror neurons, have been developed for patients with paresis, paralysis and aphasia after damage to the central nervous system (primarily strokes and traumas).
This therapy appears to be promising in Parkinson's disease, Moebius syndrome, cerebral paresis in children, phantom pain. There is a link between dysfunction of mirror neurons and autism spectrum diseases, as well as some neurodegenerative diseases such as Alzheimer's disease. Some scientists assume that mirror neurons form a new so-called “Social Nervous System”. Their role is to be further studied, evaluated and adequately applied in medical practice.
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Some scientists assume that mirror neurons form a new so-called “Social
Nervous
System
”.
The proof of their existence is a significant breakthrough in neurosciences. It is assumed that these neurons are responsible for various functions of the nervous system – empathy, imitation, prediction of others’ intentions, etc. Various new neurorehabilitation techniques, based on the concept of mirror neurons, have been developed for patients with paresis, paralysis and aphasia after damage to the central nervous system (primarily strokes and traumas). This therapy appears to be promising in Parkinson's disease, Moebius syndrome, cerebral paresis in children, phantom pain. There is a link between dysfunction of mirror neurons and autism spectrum diseases, as well as some neurodegenerative diseases such as Alzheimer's disease.
Some scientists assume that mirror neurons form a new so-called “Social Nervous System”.
Their role is to be further studied, evaluated and adequately applied in medical practice.
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The idea that these symptoms can be partially explained with dysfunction of the mirror
nervous
system
is the basis of the so-called hypothesis about the “broken mirror” [30].
They are a heterogeneous group of disorders in psychological development with common characteristics – impairment of communication skills and a limited, stereotyped, repetitive repertoire of interests and activities.
The idea that these symptoms can be partially explained with dysfunction of the mirror nervous system is the basis of the so-called hypothesis about the “broken mirror” [30].
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Medical Faculty of St Kliment Ohridski Sofia University Clinic of Functional Diagnostics of
Nervous
System
, Military Medical Academy,
Medical Faculty of St Kliment Ohridski Sofia University Clinic of Functional Diagnostics of Nervous System, Military Medical Academy,
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Starting with Introduction it is very well structured and organized in twelve chapters: Reflexes, Sensation, Motor Activity, Cranial Nerves & Specialized Sensation, Peripheral
Nervous
System
, Autonomic
Nervous
System
, Higher Cortical Functions, Cortical Syndromes, General
Kamelia Genova, Dr. Radostina Dimova, Prof. Daniela Lubenova, Ass. Prof. Pane Popov and Assoc. Prof. Boyko Stamenov, who gave their excellent contributions.
Starting with Introduction it is very well structured and organized in twelve chapters: Reflexes, Sensation, Motor Activity, Cranial Nerves & Specialized Sensation, Peripheral Nervous System, Autonomic Nervous System, Higher Cortical Functions, Cortical Syndromes, General
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In November 2017 a training seminar, organized by Academician Ekaterina Titianova – Bulgarian Coordinator of the CME programs of the World Federation of Neurology was held in the Clinic “Functional Diagnostics of the
Nervous
System
” at the Military Medical Academy.
In November 2017 a training seminar, organized by Academician Ekaterina Titianova – Bulgarian Coordinator of the CME programs of the World Federation of Neurology was held in the Clinic “Functional Diagnostics of the Nervous System” at the Military Medical Academy.
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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27.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 14, 2018, No. 2
,
,
,
Glucocorticoids and
nervous
system
plasticity.
Madalena KM, Lerch JK.
Glucocorticoids and nervous system plasticity.
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Тhe Congress of BSNCH brings together an elite, multidisciplinary team of neurologists, neurosurgeons, angiologists, endocrinologists, kinesitherapists around the discussion on innovations in ultrasound diagnostics of the
nervous
system
, modern treatment and prevention of stroke, and post-cerebrovascular accidents.
Тhe association established itself as a leader not only in Bulgaria but also in Europe. Тhe interest of nearly 200 prominent specialists from the country and abroad for this year's edition is a proof of the prestige of this forum.
Тhe Congress of BSNCH brings together an elite, multidisciplinary team of neurologists, neurosurgeons, angiologists, endocrinologists, kinesitherapists around the discussion on innovations in ultrasound diagnostics of the nervous system, modern treatment and prevention of stroke, and post-cerebrovascular accidents.
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I. PERIPHERAL
NERVOUS
SYSTEM
I. PERIPHERAL NERVOUS SYSTEM
read the entire text >>
II. CENTRAL
NERVOUS
SYSTEM
II. CENTRAL NERVOUS SYSTEM
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I. Peripheral
Nervous
System
I.
I. Peripheral Nervous System I.
Периферна нервна система
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Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
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Castro, Portugal) and diagnosis of peripheral
nervous
system
diseases such as Charcot-Marie-Tooth (D.
Alexandrov, USA), ultrasound-guided application of botulinum toxin in cervical dystonia (U. Walter, Germany), and use of contrast agents in ultrasound diagnosis and evaluation (E. Vicenzini, Italy). Among the discussed topics were also: prognostic markers for risk assessment of brain aneurysm rupture (F. Perren, Switzerland), diagnosis of retinal artery thrombosis (P.
Castro, Portugal) and diagnosis of peripheral nervous system diseases such as Charcot-Marie-Tooth (D.
Coraci, Italy) and other polyneuropathies (A. Kerasnoudis, Greece).
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Ekaterina Titianova is a Professor of Neurology, Doctor of Sciences, Head of the Clinic of Functional Diagnostics of
Nervous
System
at the Military Medical Academy, Sofia, a member of the Faculty Council and Head of the Department of Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health at the Medical Faculty of St Kliment Ohridski Sofia University.
Ekaterina Titianova is a Professor of Neurology, Doctor of Sciences, Head of the Clinic of Functional Diagnostics of Nervous System at the Military Medical Academy, Sofia, a member of the Faculty Council and Head of the Department of Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine and Public Health at the Medical Faculty of St Kliment Ohridski Sofia University.
Since 2013 she has been Academician of the Bulgarian Academy of Sciences and Arts, and since 2015 – Academician of the Serbian Royal Academy.
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new directions in ultrasound diagnostics of the
nervous
system
in Bulgaria and abroad.
new directions in ultrasound diagnostics of the nervous system in Bulgaria and abroad.
She is Principal Investigator, National Coordinator or contributor to a number of international trials in the field of stroke, multiple sclerosis, epilepsy and Parkinson’s disease. She has been a guest lecturer in Serbia, Croatia, Finland, Mexico and Georgia and chairperson in many national and international scientific events.
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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28.
NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 15, 2019, No. 1
,
,
,
Clinic of Functional Diagnostics of
Nervous
System
,
Clinic of Functional Diagnostics of Nervous System,
read the entire text >>
of
Nervous
System
Military Medical Academy
of Nervous System Military Medical Academy
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The inclusion criteria were: clinical PD diagnosis according to the criteria of the UK Parkinson's disease Society, Brain Bank [13], lack of cognitive impairment as assessed by the Mini-Mental State Examination (MMSE), no history of chronic somatic or other diseases affecting primarily or secondarily the autonomic
nervous
system
and administration of antiparkinsonian therapy alone.
The study included 55 patients with PD and 40 agerelated healthy individuals.
The inclusion criteria were: clinical PD diagnosis according to the criteria of the UK Parkinson's disease Society, Brain Bank [13], lack of cognitive impairment as assessed by the Mini-Mental State Examination (MMSE), no history of chronic somatic or other diseases affecting primarily or secondarily the autonomic nervous system and administration of antiparkinsonian therapy alone.
Most of the patients (76%) were on levodopa therapy, with an average daily dose 522.2±379.1 mg/day.
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We suppose that taking into account the age changes occurring in the autonomic
nervous
system
, it is likely that the gender differences could occur only after provocation, (both in the everyday life of the patients, after a change in the position of the body and during specialized autonomic tests).
The intergender differences we have identified in the questionnaire and in the HRV analysis in PD patients give us the reason to assume that the cardiac autonomic disorders could be genderdependent.
We suppose that taking into account the age changes occurring in the autonomic nervous system, it is likely that the gender differences could occur only after provocation, (both in the everyday life of the patients, after a change in the position of the body and during specialized autonomic tests).
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Release of emboli reaching the central
nervous
system
may cause transient ischemic attacks, acute stroke or epileptic seizures.
Myxoma is a rare tumor with a prevalence of up to 0.20% of all tumors, yet it accounts for up to 50% of the heart’s tumors, most often with symptoms in the 3rd to 6th decades of the patients life [9]. Its histological structure is benign. The tumor may remain asymptomatic or lead to death because it is most commonly localized in the valve area. The symptoms from the cardiovascular system can mimic all heart diseases and malignant processes. The most common symptoms are due to the local tumor growth and compression, causing dyspnea, pulmonary edema and other symptoms of heart failure, syncope or even sudden cardiac death [10].
Release of emboli reaching the central nervous system may cause transient ischemic attacks, acute stroke or epileptic seizures.
Consecutive ischemic strokes may occur, ranging from “silent” strokes, dementia, multi-infarct encephalopathy, to massive stroke leading to death [11]. In diagnosing myxoma, transthoracic echocardiography has a sensitivity of about 90%; the sensitivity of transesophageal echocardiography is even higher [12].
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The forum was dedicated to novelties in ultrasound diagnostics of the
nervous
system
, the control of risk factors for cerebrovascular disease, modern treatment of stroke through early recanalization (thrombolysis and/or thrombectomy), new approaches to early and late neurorehabilitation to stimulate the brain neuroplasticity and reorganization after stroke.
The forum was dedicated to novelties in ultrasound diagnostics of the nervous system, the control of risk factors for cerebrovascular disease, modern treatment of stroke through early recanalization (thrombolysis and/or thrombectomy), new approaches to early and late neurorehabilitation to stimulate the brain neuroplasticity and reorganization after stroke.
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For the first time in the Society’s history, the “Neurosonologist of the Year” prize was awarded for contributions to the ultrasound diagnostics of the
nervous
system
.
For the first time in the Society’s history, the “Neurosonologist of the Year” prize was awarded for contributions to the ultrasound diagnostics of the nervous system.
For 2018, the prize was awarded by Prof. Kurt Niederkorn to the founder and chairman of the Society Acad. Eketerina Titianova. In her thank-you speech, she shared the great success of the Neurosology and Cerebral Hemodynamics Journal, which is already referred in several international science databases: Emerging Source Citation Index of Clarivate Analytics, NLM Catalog of Pub Med, Web of Science Core Collection, VINITI Reference Journal, National Center for Information and Documentation (NCID).
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Tzvetomila Koleva (Neurology resident) at the Clinic of Functional Diagnostics of
Nervous
System
, based on materials provided by the World Federation of Neurology.
The topics of the seminar were dedicated to physiology and pathology of circadian rhythm and sleep disorders (insomnia). The latest drugs for the treatment of sleep disorders, indications of their use, and methods of controlling their efficacy were presented. The presentations were prepared by Dr. Maria Petrishka (neurologist) and Dr.
Tzvetomila Koleva (Neurology resident) at the Clinic of Functional Diagnostics of Nervous System, based on materials provided by the World Federation of Neurology.
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Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of
Nervous
System
Acad. Prof.
Ekaterina Titianova, MD, PhD, DSc Clinic of Functional Diagnostics of Nervous System
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