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11 results of 9 texts with exact phrase : 'randomized trial'.

1. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 3, 2007, No. 2 , , ,

The CAPRIE Steering Committee: A randomized trial of clopidogrel vs aspirin in patients at risk of ischemic events (CAPRIE).
The CAPRIE Steering Committee: A randomized trial of clopidogrel vs aspirin in patients at risk of ischemic events (CAPRIE).
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2. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 4, 2008, No. 2 , , ,

A double-blind, placebo-controlled randomized trial.
Lindblad B, Persson NH, Takolander R, Bergqvist D. Does low-dose acetylsalicylic acid prevent stroke after carotid surgery? A double-blind, placebo-controlled randomized trial.
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3. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 5, 2009, No. 1 , , ,

Platelet/Endothelial Biomarkers in Depressed Patients Treated With the Selective Serotonin Reuptake Inhibitor Sertraline After Acute Coronary Events The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART)
Serebruany V., Glassman A., Malinin A., Nemeroff C.; Musselman D., Zyl van L, Finke M., Krishnan R, Gaffney M., Harrison W, Califf R., O’Connor C M. Platelet/Endothelial Biomarkers in Depressed Patients Treated With the Selective Serotonin Reuptake Inhibitor Sertraline After Acute Coronary Events The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART)
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4. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 5, 2009, No. 1 , , ,

Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: preliminary results of a randomized trial.
Janicak PG, Dowd SM, Maris B et al. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: preliminary results of a randomized trial.
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5. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 6, 2010, No. 1 , , ,

Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.
Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, Czajkowski SM, DeBusk R, Hosking J, Jaffe A, Kaufmann PG, Mitchell P, Norman J, Powell LH, Raczynski JM, Schneiderman N; Enhancing Recovery in Coronary Heart Disease Patients Investigators (ENRICHD). Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.
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6. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 10, 2014, No. 1 , , ,

In a large randomized trial in patients admitted to a general intensive care unit the conventional glucose control (�10mmol/L) is compared with the intensive one (4,5-6.0 mmol/L).
isformedbasedonindependentriskfactors. Morbidity factors before CА having negative impact onCPRoutcomeare:obesity;cardiovascular diseases more frequently than those with surgical orrespiratoryetiology.Concomitantneurologic disease,traumaorelectrolytedisbalanceare associated with better survival rate [17]. Аccording to the opinion of some authors the factors during the reanimation have greater impact on the CPR outcome than the comorbidity factors before CА [6]. Risk factors during reanimation predicting the poor outcome of CPR are: initiation of CPR later than 3 min after СА; CPR duration over 15 min; СА with asystole or PЕА in adults over 75 y/a and unwitnessed СА [28]. А correlation is observed between the high levels of blood glucose after reanimationduetocardiacarrestandthe severity of the neurological deficiency. In a large randomized trial in patients admitted to a general intensive care unit the conventional glucose control (�10mmol/L) is compared with the intensive one (4,5-6.0 mmol/L). The 90-day mortality is higher in the group of patients with intensive glucose control [10]. Аccording to the recent guidelines for adult patients after ROSC the level of blood glucose shouldbekept�10mmol/L andtheintensive glucose control should be avoided due to the risk of hypoglycemia. Нyperthermia is common during the first 48 hours of IRS and associates with poor outcomes. Up to now no randomized, controlled trials have assessed the effectiveness of pyrexia control. [22].
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7. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 12, 2016, No. 1 , , ,

The MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular Treatment in the Netherlands), the SWIFT PRIME trial (Solitaire TM With the Intention For Thrombectomy as PRIMary treatment for acute ischemic stroke), the ESCAPE trial (Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times), the REVASCAT trial (Randomized Trial of Revascularization with Solitaire FR Device versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting within Eight Hours of Symptom Onset) are the biggest ones and give answers to many questions related to the treatment of acute stroke [8, 16].
The original version of the Consensus on mechanical thrombectomy in AIS was approved by the European Stroke Organization (ESO) in 2014. In 2015 this Consensus was updated with new clinical trials data. The MRCLEAN trial (Multicenter Randomized Clinical trial of Endovascular Treatment in the Netherlands), the SWIFT PRIME trial (Solitaire TM With the Intention For Thrombectomy as PRIMary treatment for acute ischemic stroke), the ESCAPE trial (Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times), the REVASCAT trial (Randomized Trial of Revascularization with Solitaire FR Device versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting within Eight Hours of Symptom Onset) are the biggest ones and give answers to many questions related to the treatment of acute stroke [8, 16].
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Проучванията MR CLEAN (Multicenter Randomized Clinical trial of Endovascular Treatment in the Netherlands), SWIFT PRIME (SolitaireTM With the Intention For Thrombectomy), ESCAPE (Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times), REVASCAT (Randomized Trial of Revascularization with Solitaire FR Device versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting within Eight Hours of Symptom Onset) са най – мащабните, които дават отговор на много от въпросите, свързани с лечението на острия исхемичен мозъчен инсулт [8, 16].
Проведени са редица проучвания, на базата на които през 2014 г. е приет консенсус за механична тромбектомия при остър исхемичен мозъчен инсулт. Същият е обновен през 2015 г., въз основа на допълнително получени данни. Проучванията MR CLEAN (Multicenter Randomized Clinical trial of Endovascular Treatment in the Netherlands), SWIFT PRIME (SolitaireTM With the Intention For Thrombectomy), ESCAPE (Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times), REVASCAT (Randomized Trial of Revascularization with Solitaire FR Device versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting within Eight Hours of Symptom Onset) са най – мащабните, които дават отговор на много от въпросите, свързани с лечението на острия исхемичен мозъчен инсулт [8, 16].
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A randomized trial of intraarterial treatment for acute ischemic stroke.
Berkhemer OA, Fransen PS, Beumer D. A randomized trial of intraarterial treatment for acute ischemic stroke.
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8. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 13, 2017, No. 1 , , ,

On the other hand, in a large, international, randomized trial (the NICE-SUGAR study), investigators found that intensive glucose control increased mortality among adult patients in the intensive care unit [31].
Based on the above-mentioned data the question is the following: High blood glucose in acute stroke: to act or not to act? Mesotten and Van den Berghe found that intensive insulin therapy in critically ill patients reduced mortality by more than 40% [29]; in 2004 Bruno et al. confirmed that good glycemic control during acute cerebral infarction in patients with diabetes mellitus type 2 was feasible and appeared to be relatively safe [30]. On the other hand, in a large, international, randomized trial (the NICE-SUGAR study), investigators found that intensive glucose control increased mortality among adult patients in the intensive care unit [31].
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9. NEUROSONOLOGY AND CEREBRAL HEMODYNAMICS, vol. 13, 2017, No. 2 , , ,

Efficacy and safety of combined intraventricular fibrinolysis with lumbar drainage for prevention of permanent shunt dependency after intracerebral hemorrhage with severe ventricular involvement: A randomized trial and individual patient data meta-analysis.
Staykov D, Kuramatsu JB, Bardutzky J, Volbers B, Gerner ST, Kloska SP, Doerfler A, Schwab S, Huttner HB. Efficacy and safety of combined intraventricular fibrinolysis with lumbar drainage for prevention of permanent shunt dependency after intracerebral hemorrhage with severe ventricular involvement: A randomized trial and individual patient data meta-analysis.
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